Region I (Connecticut, Massachusetts, Maine, New Hampshire, Rhode Island, and Vermont)
- Archdiocese of Boston(*)
- Diocese of Bridgeport
- Diocese of Burlington
- Diocese of Fall River
- Archdiocese of Hartford (*)
- Diocese of Manchester
- Diocese of Norwich
- Diocese of Portland
- Diocese of Providence
- Diocese of Springfield in Massachusetts
- Diocese of Worchester
Region II (New York)
- Diocese of Albany
- Diocese of Brooklyn
- Diocese of Buffalo
- Archdiocese of New York (*)
- Diocese of Ogdensburg
- Diocese of Rochester
- Diocese of Rockville Centre
- Diocese of Syracuse
Region III (New Jersey and Pennsylvania)
- Diocese of Allentown
- Diocese of Altoona-Johnstown
- Diocese of Camden
- Diocese of Erie
- Diocese of Greensburg
- Diocese of Harrisburg
- Diocese of Metuchen
- Archdiocese of Newark (*)
- Diocese of Paterson
- Archdiocese of Philadelphia (*)
- Diocese of Pittsburgh
- Diocese of Scranton
- Diocese of Trenton
Region IV (District of Columbia, Delaware, Maryland, Virginia, the U.S. Virgin Islands, West Virginia, and the Military Archdiocese)
- Diocese of Arlington
- Archdiocese of Baltimore (*)
- Diocese of Richmond
- Diocese of Saint Thomas in the U.S. Virgin Islands
- Archdiocese for the Military Services, USA
- Archdiocese of Washington (District of Columbia) (*)
- Diocese of Wheeling-Charleston
- Diocese of Wilmington
Region V (Alabama, Kentucky, Louisiana, Mississippi, and Tennessee)
- Diocese of Alexandria
- Diocese of Baton Rouge
- Diocese of Biloxi
- Diocese of Birmingham
- Diocese of Covington
- Diocese of Houma-Thibodaux
- Diocese of Jackson
- Diocese of Knoxville
- Diocese of Lafayette in Louisiana
- Diocese of Lake Charles
- Diocese of Lexington
- Archdiocese of Louisville (*)
- Diocese of Memphis
- Archdiocese of Mobile
- Diocese of Nashville
- Archdiocese of New Orleans (*)
- Diocese of Owensboro
- Diocese of Shreveport
Region VI (Ohio and Michigan)
- Archdiocese of Cincinnati (*)
- Diocese of Cleveland
- Diocese of Columbus
- Archdiocese of Detroit (*)
- Diocese of Gaylord
- Diocese of Grand Rapids
- Diocese of Kalamazoo
- Diocese of Lansing
- Diocese of Marquette
- Diocese of Saginaw
- Diocese of Steubenville
- Diocese of Toledo
- Diocese of Youngstown
Region VII (Illinois, Indiana, and Wisconsin)
- Diocese of Belleville
- Archdiocese of Chicago (*)
- Diocese of Evansville
- Diocese of Fort Wayne-South Bend
- Diocese of Gary
- Diocese of Green Bay
- Archdiocese of Indianapolis (*)
- Diocese of Joliet
- Diocese of La Crosse
- Diocese of Lafayette in Indiana
- Diocese of Madison
- Archdiocese of Milwaukee (*)
- Diocese of Peoria
- Diocese of Rockford
- Diocese of Springfield in Illinois
- Diocese of Superior
Region VIII (Minnesota, North Dakota, and South Dakota)
- Diocese of Bismarck
- Diocese of Crookston
- Diocese of Duluth
- Diocese of Fargo
- Diocese of New Ulm
- Diocese of Rapid City
- Diocese of Saint Cloud
- Archdiocese of Saint Paul and Minneapolis (*)
- Diocese of Sioux Falls
- Diocese of Winona-Rochester
Region IX (Iowa, Kansas, Missouri, and Nebraska)
- Diocese of Davenport
- Diocese of Des Moines
- Diocese of Dodge City
- Archdiocese of Dubuque (*)
- Diocese of Grand Island
- Diocese of Jefferson City
- Archdiocese of Kansas City in Kansas (*)
- Diocese of Kansas City-Saint Joseph
- Diocese of Lincoln
- Archdiocese of Omaha (*)
- Archdiocese of Saint Louis (*)
- Diocese of Salina
- Diocese of Sioux City
- Diocese of Springfield-Cape Girardeau
- Diocese of Wichita
Region X (Arkansas, Oklahoma, and Texas)
- Diocese of Amarillo
- Diocese of Austin
- Diocese of Beaumont
- Diocese of Brownsville
- Diocese of Corpus Christi
- Diocese of Dallas
- Diocese of El Paso
- Diocese of Fort Worth
- Archdiocese of Galveston-Houston (*)
- Diocese of Laredo
- Diocese of Little Rock
- Diocese of Lubbock
- Archdiocese of Oklahoma City (*)
- Diocese of San Angelo
- Archdiocese of San Antonio (*)
- Diocese of Tulsa
- Diocese of Tyler
- Diocese of Victoria
Region XI (California, Hawaii, and Nevada)
- Diocese of Fresno
- Diocese of Honolulu
- Diocese of Las Vegas
- Archdiocese of Los Angeles (*)
- Diocese of Monterey
- Diocese of Oakland
- Diocese of Orange
- Diocese of Reno
- Diocese of Sacramento
- Diocese of San Bernardino
- Diocese of San Diego
- Archdiocese of San Francisco (*)
- Diocese of San Jose
- Diocese of Santa Rosa
- Diocese of Stockton
Region XII (Alaska, Idaho, Montana, Oregon, and Washington)
- Archdiocese of Anchorage-Juneau (*)
- Diocese of Baker
- Diocese of Boise
- Diocese of Fairbanks
- Diocese of Great Falls-Billings
- Diocese of Helena
- Diocese of Juneau
- Archdiocese of Portland (*)
- Archdiocese of Seattle (*)
- Diocese of Spokane
- Diocese of Yakima
Region XIII (Arizona, Colorado, New Mexico, Utah, and Wyoming)
- Diocese of Cheyenne
- Diocese of Colorado Springs
- Archdiocese of Denver (*)
- Diocese of Gallup
- Diocese of Las Cruces
- Diocese of Phoenix
- Diocese of Pueblo
- Diocese of Salt Lake City
- Archdiocese of Santa Fe (*)
- Diocese of Tucson
Region XIV (Florida, Georgia, North Carolina, South Carolina)
- Archdiocese of Atlanta (*)
- Diocese of Charleston
- Diocese of Charlotte
- Archdiocese of Miami (*)
- Diocese of Orlando
- Diocese of Palm Beach
- Diocese of Pensacola-Tallahassee
- Diocese of Raleigh
- Diocese of Saint Augustine
- Diocese of Saint Petersburg
- Diocese of Savannah
- Diocese of Venice
These regions typically include two or more Metropolitan Archdioceses (*) and several Dioceses across one or more States.